| 发明名称 |
In-vivo screening method |
| 摘要 |
<p>The present invention relates to a method of screening for a substance that increases pelvic floor muscles contraction, comprising increasing an intravesical pressure after bilateral transection of the hypogastric nerve and pudendal nerve of an animal, and (i) measuring a closure response in the urinary tract, rectum or vagina observed at that time, or (ii) measuring the leak point pressure at that time.</p> |
| 申请公布号 |
EP2727585(A1) |
申请公布日期 |
2014.05.07 |
| 申请号 |
EP20130195352 |
申请日期 |
2007.05.15 |
| 申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
SHIRAI, JUNYA;KUSUMOTO, TOMOKAZU;NAGAMIYA, HIROYUKI;KAMO, IZUMI |
| 分类号 |
A61K31/00;A61K31/4353;A61K31/553;A61K49/00;A61P3/04;A61P13/02;A61P15/02;A61P21/00;A61P43/00;C07D223/16;C07D487/04;C07D498/04;C07D519/00;G01N33/94 |
主分类号 |
A61K31/00 |
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