发明名称 |
METHOD FOR STUDYING TRANSPORT OF AN AGENT ACROSS A BILAYER MEMBRANE IN BIOANALYTICAL SENSOR APPLICATIONS |
摘要 |
The present invention provides a method for studying transport of an agent across a membrane comprising the steps a) providing at least one surface with a bilayer structure tethered to the surface, said bilayer structure comprising a detection volume, b) contacting the bilayer with at least one agent to be analyzed, and c) detecting a change in refractive index in the detection volume resulting from transportation of the agent across the membrane. Further there is provided a device comprising a) at least one surface, b) at least one bilayer structure tethered to the surface, and c) at least one sensor capable of detecting a change in refractive index in a detection volume, wherein the bilayer structure encloses a first volume of the detection volume and wherein the volume not enclosed by the bilayer structure but within the detection volume is a second volume and wherein the ratio between the first volume and second volume is above about 0.001. |
申请公布号 |
EP2250502(B1) |
申请公布日期 |
2014.05.07 |
申请号 |
EP20090709128 |
申请日期 |
2009.02.06 |
申请人 |
BIO-RAD LABORATORIES, INC. |
发明人 |
HOEOEK, FREDRIK;BRAENDEN, MAGNUS;TABAEI, SEYED |
分类号 |
G01N33/50;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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