| 发明名称 |
Inhibition of the interaction between 5T4 oncofoetal glycoproteins and CXC chemokine receptors as a method of identifying chemotaxis inhibitors |
| 摘要 |
Methods and agents are disclosed based on the finding that 5T4 interacts with CXCR4 in the cell membrane to form a complex, and that the 5T4 transmembrane region is involved in the promotion of CXCR4 membrane expression and chemotactic response. |
| 申请公布号 |
US8715947(B2) |
申请公布日期 |
2014.05.06 |
| 申请号 |
US201013502893 |
申请日期 |
2010.10.20 |
| 申请人 |
STERN PETER L.;SAHA VASKAR;CANCER RESEARCH TECHNOLOGY LIMITED |
发明人 |
STERN PETER L.;SAHA VASKAR |
| 分类号 |
G01N33/567;G01N33/574 |
主分类号 |
G01N33/567 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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