发明名称 |
Method for enantioselective hydrogenation of chromenes |
摘要 |
A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained. |
申请公布号 |
US8716497(B2) |
申请公布日期 |
2014.05.06 |
申请号 |
US201213608330 |
申请日期 |
2012.09.10 |
申请人 |
SETCHELL KENNETH DAVID REGINALD;SOROKIN VICTOR DMITRIEVICH;CHILDREN'S HOSPITAL MEDICAL CENTER;AUSIO PHARMACEUTICALS, INC. |
发明人 |
SETCHELL KENNETH DAVID REGINALD;SOROKIN VICTOR DMITRIEVICH |
分类号 |
C07D311/00 |
主分类号 |
C07D311/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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