摘要 |
There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterised in that the coarse fraction possesses a greater mass median aerodynamic diameter (MMDA) than the fine fraction. There is also described a method of a method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by the co-administration with a substantially coarse active ingredient. |