发明名称 |
IMIDAZOLE DERIVATIVES AS FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
Imidazole derivatives of formula (I) wherein R1, R2a, R2b, A, V and W are as defined in the description, as inhibitors of fructose-1 ,6-bisphosphatase, their preparation process and their use in the prevention or treatment of diabetes, and other diseases where the inhibition of gluconeogenesis, control of blood glucose levels, reduction in glycogen stores, or reduction in insulin levels is beneficial and diseases related to the insulin resistance syndrome. |
申请公布号 |
CA2617378(C) |
申请公布日期 |
2014.05.06 |
申请号 |
CA20062617378 |
申请日期 |
2006.07.19 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
CARNIATO, DENIS;MOINET, GERARD;BOTTON, GERARD;ARBELLOT DE VACQUEUR, ANNICK;AUDET, ANNICK |
分类号 |
C07D233/54;A61K31/4164;A61K31/4245;A61K31/427;A61K31/4709;A61P3/00;A61P9/00;C07D233/64 |
主分类号 |
C07D233/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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