发明名称 |
Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
摘要 |
A method provides an index that is indicative of the state of a subject, as to a biological condition, based on a sample from the subject. An embodiment of this method includes: deriving from the sample a profile data set, the profile data set including a plurality of members, each member being a quantitative measure of the amount of a distinct RNA or protein constituent in a panel of constituents selected so that measurement of the constituents enables evaluation of the biological condition; and in deriving the profile data set, achieving such measure for each constituent under measurement conditions that are substantially repeatable; and applying values from the profile data set to an index function that provides a mapping from an instance of a profile data set into a single-valued measure of biological condition, so as to produce an index pertinent to the biological condition of the subject. |
申请公布号 |
US8718946(B2) |
申请公布日期 |
2014.05.06 |
申请号 |
US201113239070 |
申请日期 |
2011.09.21 |
申请人 |
BEVILACQUA MICHAEL;CHERONIS JOHN;TRYON VICTOR;BANKAITIS-DAVIS DANUTE;LIFE TECHNOLOGIES CORPORATION |
发明人 |
BEVILACQUA MICHAEL;CHERONIS JOHN;TRYON VICTOR;BANKAITIS-DAVIS DANUTE |
分类号 |
G06F19/00;C12Q1/68;G01N33/574;G01N33/68;G06F19/18;G06F19/20;G06Q50/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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