发明名称 SYNTHETIC OPLOPHORUS LUCIFERASES WITH ENHANCED LIGHT OUTPUT
摘要 A polynucleotide encoding a modified luciferase polypeptide. The modified luciferase polypeptide has at least 60% amino acid sequence identity to a wild-type Oplophorus luciferase and includes at least one amino acid substitution at a position corresponding to an amino acid in a wild-type Oplophorus luciferase of SEQ ID NO:1. The modified luciferase polypeptide has at least one of enhanced luminescence, enhanced signal stability, and enhanced protein stability relative to the wild-type Oplophorus luciferase.
申请公布号 US2014120548(A1) 申请公布日期 2014.05.01
申请号 US201314053252 申请日期 2013.10.14
申请人 PROMEGA CORPORATION 发明人 ENCELL LANCE P.;HALL MARY;OTTO PAUL;VIDUGIRIS GEDIMINAS;WOOD KEITH V.;WOOD MONIKA G.;ZIMMERMAN KRISTOPHER
分类号 C12Q1/66 主分类号 C12Q1/66
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