发明名称 QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
摘要 Compounds that inhibit PI3Kδactivity, including compounds that selectively inhibit PI3Kδactivity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδplays a role in leukocyte function, using the compounds also are disclosed.
申请公布号 US2014121223(A1) 申请公布日期 2014.05.01
申请号 US201314049154 申请日期 2013.10.08
申请人 ICOS CORPORATION 发明人 FOWLER KERRY W.;HUANG DANWEN;KESICKI EDWARD A.;OOI HUA CHEE;OLIVER AMY;RUAN FUQIANG;TREIBERG JENNIFER;PURI KAMAL DEEP
分类号 C07D473/34;A61K31/517;A61K31/519;C07D239/91;C07D473/16;C07D487/04 主分类号 C07D473/34
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