发明名称 MONITORING AND INHIBITING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BY MODULATING HMGB1 DEPENDENT TRIGGERING OF HIV-1 REPLICATION AND PERSISTENCE
摘要 Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
申请公布号 US2014120525(A1) 申请公布日期 2014.05.01
申请号 US201314073112 申请日期 2013.11.06
申请人 INSTITUT PASTEUR 发明人 GOUGEON MARIE-LISE;SAIDI HELA;MELKI MARIE-THERESE;POIRIER-BEAUDOIN BEATRICE;SEFFER VALERIE
分类号 G01N33/569 主分类号 G01N33/569
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