METHOD OF PREVENTING DEVELOPMENT OF PSORIATIC LESIONS

摘要

A method of inhibiting onset of, or preventing development of, a psoriatic lesion in a patient having psoriasis is disclosed. The method comprises administering to a patient having psoriasis an effective amount of an agent that inhibits NF -KB activity to inhibit onset of or prevent development of psoriatic lesions. A method of treating an early stage psoriatic lesion on a patient by contacting the early stage psoriatic lesion with an effective amount of an agent that inhibits NF -KB activity, whereby said contacting inhibits development of the early stage psoriatic lesion is also disclosed. Both transgenic and nontransgenic approaches are contemplated.