| 发明名称 |
COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES |
| 摘要 |
<p>The present invention relates to compounds useful for treating parasitic diseases, which are infectious diseases caused or transmitted by a parasite. Compounds of the invention are particularly active against the causative pathogens in malaria. Such compounds are selective inhibitors of parasitic histone deacetylase (PfHDAC) and suppress the growth of parasites, such as Plasmodium falciparum, at a lower concentration than the concentration required for the inhibition of the growth of mammalian cells.</p> |
| 申请公布号 |
ITRM20120530(A1) |
申请公布日期 |
2014.05.01 |
| 申请号 |
IT2012RM00530 |
申请日期 |
2012.10.31 |
| 申请人 |
C.N.C.C.S. S.C.A.R.L. COLLEZIONE NA ZIONALE DEI CO;IRBM SCIENCE PARK S.P.A. |
发明人 |
ALTAMURA SERGIO;BIANCOFIORE ILARIA;BRESCIANI ALBERTO;FERRIGNO FEDERICA;HARPER STEVEN;LAUFER RALPH;MALANCONA SAVINA;MONTEAGUDO EDITH;NIZI EMANUELA;ONTORIA ONTORIA JESUS MARIA;ORSALE MARIA VITTORIA;PAONESSA GIACOMO;PONZI SIMONA;SUMMA VINCENZO;VENEZIANO MARIA |
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