发明名称 |
Conditionally immortalized long-term stem cells and methods of making and using such cells |
摘要 |
Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of using such cells, and methods to identify compounds related to cell differentiation and development or to treat diseases, using such cells. A mouse model of acute myeloid leukemia (AML) and cells and methods related to such mouse model are also described. |
申请公布号 |
AU2006304392(B2) |
申请公布日期 |
2014.05.01 |
申请号 |
AU20060304392 |
申请日期 |
2006.10.18 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO;NATIONAL JEWISH HEALTH |
发明人 |
JOHNSON, SARA;CAMBIER, JOHN;REFAELI, YOSEF;TURNER, BRIAN CURTIS |
分类号 |
A01N63/00;A01K67/00;A01K67/033;A01N65/00;A61K48/00;C07H21/02;C07H21/04;C12N5/00;C12N5/02;C12N5/0735;C12N15/86;G01N33/00 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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