发明名称 |
THE SYNTHESIS OF TETRAHYDROISOQUINOLINES FROM 2-METHYL-1-PHENYL SUBSTITUTED INDENES |
摘要 |
<p>A procedure for the synthesis of tetrahydroisoquinolines from 2-methyl-l -phenyl substituted indene is described. The process invovles the use of osmium tetroxide to cleave the indene double bond forming the keto aldehyde product, which is then combined with a substituted amine forming the substituted isoquinoline. Isoquinolines can be useful as industrial products in the chemical, agrochemical, oil and gas industry, as well as useful as medicaments in the pharmaceutical industry.</p> |
申请公布号 |
WO2014064476(A1) |
申请公布日期 |
2014.05.01 |
申请号 |
WO2012IB02070 |
申请日期 |
2012.10.24 |
申请人 |
ROSOCHA, GREGORY |
发明人 |
ROSOCHA, GREGORY;BATEY, ROBERT, A. |
分类号 |
C07D217/04;C01B11/22;C01G55/00;C07C13/465 |
主分类号 |
C07D217/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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