| 摘要 |
<p> Provided is a therapeutic agent for neurodegenerative disorders and psychiatric disorders related to mGluR5, the therapeutic agent comprising a compound represented by formula (I) or a pharmaceutically acceptable salt of the same (in the formula, R1 represents a halogen, methyl or cyano, and R2 and R3 each independently represents a hydrogen atom, a halogen, a C1-3 alkyl, a C1-3 alkoxy or a cyano), having the function of a metabotropic glutamic acid receptor sub-type 5 (mGluR5) negative modulator, having oral absorption properties with excellent pharmacokinetics, having high bioavailability and excellent stability.</p> |
