发明名称 |
TRUNCATED VARIANT OF THE MAMMALIAN TARGET FOR RAPAMYCIN (mTOR) PROTEIN |
摘要 |
The invention relates to mTORbeta, a splice form of mTOR, nucleic acids encoding mTOR beta, and antibodies against mTOR beta. The invention also relates to methods of producing mTOR beta and methods of screening for an agent that modulates mTOR beta expression and/or activity. The invention further relates to a method of treating a disease associated with aberrant expression of mTOR beta by administration of an agent that alters mTOR activity and/or expression. |
申请公布号 |
US2014120099(A1) |
申请公布日期 |
2014.05.01 |
申请号 |
US201314035634 |
申请日期 |
2013.09.24 |
申请人 |
UCL BUSINESS PLC;LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
NEMAZANYY IVAN;PANASYUK GANNA;ZHYVOLOUP ALEXANDER;WATERFIELD MICHAEL;GOUT IVAN |
分类号 |
C12N9/12;C12Q1/48 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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