| 发明名称 |
METHODS AND COMPOSITIONS FOR 6-PHOSPHOGLUCONATE DEHYDROGENASE (6-PGD) AS A TARGET FOR LUNG CANCER THERAPY |
| 摘要 |
<p>The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing a proliferative disease that result in dysregulation of 6-phosphogluconate dehydrogenase. In particular, the methods and compositions include treatment of gefitinib/erlotinib resistant proliferative diseases such as lung cancer using a 6-phosphogluconate dehydrogenase antagonist.</p> |
| 申请公布号 |
WO2013152186(A8) |
申请公布日期 |
2014.05.01 |
| 申请号 |
WO2013US35268 |
申请日期 |
2013.04.04 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. |
发明人 |
SUKHATME, VIKAS, P.;CHAN, CHUNKONG, BARDEN |
| 分类号 |
C12Q1/32 |
主分类号 |
C12Q1/32 |
| 代理机构 |
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