FUNGAL NANOPARTICLES AND METHODS OF MAKING AND USING THEREOF

摘要

Nanoparticles produced by and isolated from a fungus of the genus Arthrobotrys are disclosed and can comprise at least about 1% by weight of a glycosaminoglycan. Also disclosed are fractions obtained from the nanoparticles. Methods of preparing and isolating these nanoparticles and fractions are also disclosed. The disclosed nanoparticles and fractions are suitable as carries in a variety of medical formulations. Thus, in a further aspect, the present disclosure relates to compositions comprising the disclosed nanoparticles and fractions with carriers, excipients, and/or therapeutic agents. Methods of treating subjects with these compositions are also disclosed.