发明名称 |
Use of toll-like receptor and agonist for treating cancer |
摘要 |
<p>The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin resulting in a cis and in-trans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-ĸB apoptosis pathway.</p> |
申请公布号 |
AU2010303464(B2) |
申请公布日期 |
2014.05.01 |
申请号 |
AU20100303464 |
申请日期 |
2010.10.06 |
申请人 |
ROSWELL PARK CANCER INSTITUTE;PANACELA LABS, INC. |
发明人 |
GUDKOV, ANDREI V. |
分类号 |
C12N15/63 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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