发明名称 |
ANTI-CD154 ANTIBODIES HAVING IMPAIRED FCR BINDING AND/OR COMPLEMENT BINDING PROPERTIES AND THE USE THEREOF IN IMMUNE THERAPIES |
摘要 |
Improved anti-CD154 antibodies are provided herein which have ablated FcR binding. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein. |
申请公布号 |
WO2012138768(A3) |
申请公布日期 |
2014.05.01 |
申请号 |
WO2012US32183 |
申请日期 |
2012.04.04 |
申请人 |
TRUSTEES OF DARTMOUTH COLLEGE;NOELLE, RANDOLPH, J. |
发明人 |
NOELLE, RANDOLPH, J. |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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