| 摘要 |
<p>[Problem] To develop an in vitro infection-evaluation model useful in the explication of a bacterial infection mechanism. [Solution] (1) An infection-evaluation method characterized by containing: an insertion step for inserting an in vivo indwelling object such as a needle or a catheter into a gel culture medium; an application step for applying bacteria in the vicinity of the insertion location of the inserted in vivo indwelling object or the vicinity of the exit location thereof; a cultivation step for cultivating the gel culture medium after the application step; and an evaluation step for evaluating a change in the appearance of the gel culture medium after the cultivation step. (2) An infection-evaluation model for implementing the infection-evaluation method described in (1), the infection-evaluation model being characterized by being provided with a gel culture medium, and in that the gel culture medium is provided with an insertion section into which it is possible to insert an in vivo indwelling object such as a needle or a catheter, the spread of the bacterial infection causes a change to the appearance of the gel culture medium, and it is possible to evaluate the spread of the bacterial infection by evaluating this change in appearance.</p> |
