发明名称 CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS FOR METABOLIC DISORDERS
摘要 Disclosed are carboxamide, sulfonamide and amine compounds of formula (I)or a pharmaceutically acceptable salt, prodrug, solvate, hydrate or N-oxides thereof, where B, A ring system, R, R, R, E, Q and y are as described herein. The invention further relates to pharmaceutical compositions and to methods for using said compounds. The compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
申请公布号 EA019509(B1) 申请公布日期 2014.04.30
申请号 EA20100070619 申请日期 2008.11.17
申请人 RIGEL PHARMACEUTICALS, INC. 发明人 HONG HUI;XU XIANG;YU JIAXIN;SINGH RAJINDER;DARWISH IHAB, S.;THOTA SAMBAIAH
分类号 C07D211/46;A61K31/4427;A61K31/4523;A61P3/00;A61P9/00;C07D211/58;C07D401/12;C07D401/14;C07D405/14;C07D409/14 主分类号 C07D211/46
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