摘要 |
Disclosed are carboxamide, sulfonamide and amine compounds of formula (I)or a pharmaceutically acceptable salt, prodrug, solvate, hydrate or N-oxides thereof, where B, A ring system, R, R, R, E, Q and y are as described herein. The invention further relates to pharmaceutical compositions and to methods for using said compounds. The compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions. |