发明名称 SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINOL DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE10A)
摘要 The invention relates to compounds of the formula wherein R′, R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.
申请公布号 ZA201306416(B) 申请公布日期 2014.04.30
申请号 ZA20130006416 申请日期 2013.08.26
申请人 ALLERGAN INC;EXONHIT THERAPEUTICS SA 发明人 DONELLO JOHN E;YANG RONG;LEBLOND BERTRAND;BEAUSOLEIL ERIC;CASAGRANDE ANNE-SOPHIE;DESIRE LAURENT J R;PANDO MATTHEW P;CHAUVIGNAC CEDRIC;TAVERNE THIERRY
分类号 A61K;A61P;C07D 主分类号 A61K
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