Derivados de amidas aromáticas como inhibidores de la cinasa C-KIT
摘要
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a ompound of the present invention:
or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
申请公布号
ES2458291(T3)
申请公布日期
2014.04.30
申请号
ES20110161399T
申请日期
2007.04.19
申请人
JANSSEN PHARMACEUTICA NV
发明人
ILLIG, CARL R.;BALLENTINE, SHELLEY K.;CHEN, JINGSHENG;MEEGALLA, SANATH K.;WALL, MARK J.;WILSON, KENNETH J.;RUDOLPH, M. JONATHAN;DESJARLAIS, RENEE L.;MOLLOY, CHRISTOPHER J.;MANTHEY, CARL L.;FLORES, CHRISTOPHER