发明名称 |
METHOD FOR ANALYZING MUCIN 1 USING PROBE CAPABLE OF BINDING TO 3'-SULFONATED CORE 1 CARBOHYDRATE CHAIN, AND METHOD FOR DETECTING OR MONITORING BREAST CANCER |
摘要 |
The purpose of the present invention is to provide a method for detecting even mucin 1 derived from breast cancer, which cannot be detected by a CA15-3 measurement method. The purpose can be achieved by a method for analyzing the mucin 1 having a Sulfo-3Gal²1-3GalNAc-R carbohydrate chain, including: a step of bringing a 3' sulfonated core 1 carbohydrate chain binding probe capable of binding to the Sulfo-3Gal²1-3GalNAc-R carbohydrate chain into contact with a sample to be tested; a step of bringing a 3' sulfonated core 1 carbohydrate chain mucin 1 peptide binding probe capable of binding to the mucin 1 having a Sulfo-3Gal²1-3GalNAc-R carbohydrate chain or a mucin 1 binding probe capable of binding to a mucin 1 into contact with the sample to be tested; and a step of detecting a conjugate of the mucin 1 having a Sulfo-3Gal²1-3GalNAc-R carbohydrate chain and probe. |
申请公布号 |
KR20140051249(A) |
申请公布日期 |
2014.04.30 |
申请号 |
KR20147001128 |
申请日期 |
2012.06.15 |
申请人 |
TOKYO INSTITUTE OF TECHNOLOGY;YAMAGUCHI UNIVERSITY |
发明人 |
YAMASHITA KATSUKO;IDEO HIROKO;HINODA YUJI |
分类号 |
G01N33/53;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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