发明名称 |
YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING A MULTIDRUG EFFLUX PUMP GENE |
摘要 |
<p>Increasing tolerance to butanol in yeast has been accomplished by decreasing activity of Pdr5p encoded by an endogenous PDR5 gene. A deletion mutation of the PDR5 gene led to improved growth yield in the presence of butanol. Yeast cells with reduced Pdr5p activity, or other multidrug resistance ATP-binding cassette transporter protein activity encoded by CDR1 or BFR1, and a butanol biosynthetic pathway may be used for improved butanol production.</p> |
申请公布号 |
EP2401360(B1) |
申请公布日期 |
2014.04.30 |
申请号 |
EP20100708045 |
申请日期 |
2010.03.01 |
申请人 |
BUTAMAX(TM) ADVANCED BIOFUELS LLC |
发明人 |
VAN DYK, TINA, K. |
分类号 |
C12N1/16;C12N1/18;C12P7/16 |
主分类号 |
C12N1/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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