| 发明名称 |
NOVEL SUBSTITUTED INDOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS. |
| 摘要 |
<p>The present invention is concerned with novel substituted indole derivatives of Formula (I) wherein R1, R2, R3, A1, A2, A3, Y and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p> |
| 申请公布号 |
MX2014000626(A) |
申请公布日期 |
2014.04.30 |
| 申请号 |
MX20140000626 |
申请日期 |
2012.07.12 |
| 申请人 |
JANSSEN PHARMACEUTICALS, INC. |
发明人 |
GIJSEN, HENRICUS JACOBUS MARIA;BISCHOFF, FRANÇOIS PAUL;BERTHELOT, DIDIER JEAN-CLAUDE;VELTER, ADRIANA INGRID;PIETERS, SERGE MARIA ALOYSIUS;MINNE, GARRETT BERLOND |
| 分类号 |
C07D487/04;A61K31/5383;A61P25/28;C07D498/04 |
主分类号 |
C07D487/04 |
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