METHOD FOR GENERATING A MOUSE HOMOZYGOUS FOR A GENETIC MODIFICATION
摘要
Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant or compete contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
申请公布号
EP1802193(B1)
申请公布日期
2014.04.30
申请号
EP20050807480
申请日期
2005.10.19
申请人
REGENERON PHARMACEUTICALS, INC.
发明人
POUEYMIROU, WILLIAM;DECHIARA, THOMAS, M.;AUERBACH, WOJTEK;FRENDEWEY, DAVID;VALENZUELA, DAVID, M.
