发明名称 BRIDGE PIPERIDINE DERIVATIVES
摘要 The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of &bgr;-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
申请公布号 ZA201305322(B) 申请公布日期 2014.04.30
申请号 ZA20130005322 申请日期 2013.07.15
申请人 F.HOFFMANN LA ROCHE AG 发明人 BAUMANN KARLHEINZ;LLIMBERG ANJA;THOMAS ANDREW;GREEN LUKE;LUEBBERS THOMAS
分类号 A61K;A61P;C07D 主分类号 A61K
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