发明名称 |
Methods and kits for predicting the responsiveness of hepatocellular carcinoma patients to 5-fluorouracil-based combination chemotherapy |
摘要 |
Disclosed herein is a method for identifying single nucleotide polymorphisms of a target nucleic acid for predicting whether a patient suffering from hepatocellular carcinoma will respond to a 5-fluorouracil (5-FU)-based combination chemotherapy. In some embodiments, biological sample derived from the patient is processed to determine the presence of a T/T genotype of rs9679162 GALNT14 gene. The presence of the above-identified genotype is an indication that the patient is responsive to the 5-FU-based combination chemotherapy. |
申请公布号 |
US8709720(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US201213411306 |
申请日期 |
2012.03.02 |
申请人 |
YEH CHAU-TING;LIANG KUNG-HAO |
发明人 |
YEH CHAU-TING;LIANG KUNG-HAO |
分类号 |
C12P19/34;A61K48/00;C07H21/04;C12Q1/68 |
主分类号 |
C12P19/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|