发明名称 Antisense modulation of C-reactive protein expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided.
申请公布号 US8710023(B2) 申请公布日期 2014.04.29
申请号 US201113309835 申请日期 2011.12.02
申请人 CROOKE ROSANNE M.;GRAHAM MARK J.;ISIS PHARMACEUTICALS, INC. 发明人 CROOKE ROSANNE M.;GRAHAM MARK J.
分类号 A61K31/70;C12N15/09;A61K31/7088;A61K38/00;A61K48/00;A61P9/00;A61P9/10;C07H21/02;C07H21/04;C12N15/113;C12Q1/68 主分类号 A61K31/70
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