发明名称 |
Antisense modulation of C-reactive protein expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided. |
申请公布号 |
US8710023(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US201113309835 |
申请日期 |
2011.12.02 |
申请人 |
CROOKE ROSANNE M.;GRAHAM MARK J.;ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE ROSANNE M.;GRAHAM MARK J. |
分类号 |
A61K31/70;C12N15/09;A61K31/7088;A61K38/00;A61K48/00;A61P9/00;A61P9/10;C07H21/02;C07H21/04;C12N15/113;C12Q1/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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