发明名称 MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY
摘要 Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 -R 3 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and a Heteroaryl Compound provided herein for use in a method of treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
申请公布号 SG2014006852(A) 申请公布日期 2014.04.28
申请号 SG20140006852 申请日期 2009.10.27
申请人 SIGNAL PHARMACEUTICALS, LLC 发明人 ELSNER, JAN;HARRIS, ROY, L.;LEE, BRANDEN;MORTENSEN, DEBORAH;PACKARD, GARRICK;PAPA, PATRICK;PERRIN-NINKOVIC, SOPHIE;RIGGS, JENNIFER;SANKAR, SABITA;SAPIENZA, JOHN;SHEVLIN, GRAZIELLA;TEHRANI, LIDA;XU, WEIMING;ZHAO, JINGJING;PARNES, JASON;MADAKAMUTIL LOUI;FULTZ KIMBERLY;NARLA, RAMA K.
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