PHARMACEUTICAL COMBINATIONS OF AN ANGIOTENSIN RECEPTOR ANTAGONIST AND AN NEP INHIBITOR

摘要

The invention relates to a dual-acting compound having the sum formula [(( S )- N -valeryl- N- {[2'-(1 H -tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine) ((2 R ,4 S )-5-biphenyl4-yl-5-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester)]Na1-3 x H2O, wherein x is 0 to 3, and related invention embodiments. The dual-acting compound is an angiotensin receptor blocker and a neutral endopeptidase inhibitor.