| 摘要 |
PROBLEM TO BE SOLVED: To provide a breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system.SOLUTION: A dry powder inhaler 100 can be provided with or without a unit dose cartridge 150 for using with the inhaler 100. The inhaler 100 and/or cartridge 150 can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler 100 is compact; can be provided in various shapes and sizes, colors, and comprises a housing 120, a mouthpiece 130, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, is relatively easy to use, and can be reusable or disposable. |
