发明名称 PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS
摘要 The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.
申请公布号 WO2014060112(A1) 申请公布日期 2014.04.24
申请号 WO2013EP03146 申请日期 2013.10.18
申请人 ORIGENIS GMBH 发明人 ALMSTETTER, MICHAEL;THORMANN, MICHAEL;TREML, ANDREAS;TRAUBE, NADINE
分类号 C07D487/04;A61K31/519;A61P1/00;A61P3/00;A61P9/00;A61P11/00;A61P17/00;A61P19/00;A61P25/00;A61P25/16;A61P27/02;A61P29/00;A61P35/00;A61P37/00;C07D519/00 主分类号 C07D487/04
代理机构 代理人
主权项
地址