发明名称 COMPOSITIONS COMPRISING BIOMEMBRANE SEALING AGENT FOR TREATMENT OF NEURONAL INJURY, AND METHODS OF USE
摘要 PROBLEM TO BE SOLVED: To provide compositions, kits and methods for treatment of neuronal injuries and pains.SOLUTION: A pharmaceutical composition for injection comprises: a biomembrane sealing agent such as PEG; and a bioactive agent such as a magnesium compound. The biomembrane sealing agent and/or the bioactive agent are delivered by intravenous administration, intramuscular administration, intrathecal administration, subcutaneous administration, epidural administration, parenteral administration, or direct application to a site of pathological conditions or to the vicinity thereof, and by any method selected among groups each consisting of combinations of them. Otherwise, the biomembrane sealing agent and/or the bioactive agent may be delivered from a pump or an implant. For the pharmaceutical composition, at least one kind of magnesium compound is selected from a group consisting of: magnesium sulfate; magnesium chloride; magnesium gluconate; magnesium ATP; and combinations of them.
申请公布号 JP2014074061(A) 申请公布日期 2014.04.24
申请号 JP20130270024 申请日期 2013.12.26
申请人 WARSAW ORTHOPAEDIC INC 发明人 ROY JOSEE;MCKAY WILLIAM F;MARX JEFFREY C
分类号 A61K33/06;A61K9/08;A61K31/77;A61K47/34;A61P25/00;A61P25/28;A61P43/00 主分类号 A61K33/06
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