USE OF HYDROXYTIROSOL AND DERIVATIVES THEREOF AS QUORUM QUENCHERS

摘要

Herein is described the quorum quenching activity of compounds of formula (I) or (II) such as hydroxytyrosol (HT), hydroxytyrosol acetate (HTA), 3,4-dihydroxyphenylacetic acid (DOPAC) and derivatives thereof. It is also described their use in the treatment of bacterial infections or a disorder associated with biofilm formation in a subject, associated with quorum sensing caused by pathogenic bacteria as well as their use in the manufacturing of food, foodpakage, medical devices and pharmaceutical compositions.