发明名称 SUBSTITUTED CARBAMATE COMPOUNDS AND THEIR USE AS TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL ANTAGONISTS
摘要 The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.
申请公布号 CA2879256(A1) 申请公布日期 2014.04.24
申请号 CA20132879256 申请日期 2013.10.14
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BROTHERTON-PLEISS, CHRISTINE E.;CHEN, ZHI;ERICKSON, SHAWN DAVID;KIM, KYUNGJIN;LI, HONGJU;LOVEY, ALLEN JOHN;QIAN, YIMIN;SO, SUNG-SAU;WOVKULICH, PETER MICHAEL;YI, LIN
分类号 C07D207/06;A61K31/40;C07D211/14;C07D211/18;C07D211/22;C07D211/28;C07D211/32;C07D211/34;C07D211/38;C07D211/42;C07D211/54;C07D223/04;C07D401/04;C07D401/12;C07D413/04 主分类号 C07D207/06
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