发明名称 |
SUBSTITUTED CARBAMATE COMPOUNDS AND THEIR USE AS TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL ANTAGONISTS |
摘要 |
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel. |
申请公布号 |
CA2879256(A1) |
申请公布日期 |
2014.04.24 |
申请号 |
CA20132879256 |
申请日期 |
2013.10.14 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BROTHERTON-PLEISS, CHRISTINE E.;CHEN, ZHI;ERICKSON, SHAWN DAVID;KIM, KYUNGJIN;LI, HONGJU;LOVEY, ALLEN JOHN;QIAN, YIMIN;SO, SUNG-SAU;WOVKULICH, PETER MICHAEL;YI, LIN |
分类号 |
C07D207/06;A61K31/40;C07D211/14;C07D211/18;C07D211/22;C07D211/28;C07D211/32;C07D211/34;C07D211/38;C07D211/42;C07D211/54;C07D223/04;C07D401/04;C07D401/12;C07D413/04 |
主分类号 |
C07D207/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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