发明名称 PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T
摘要 The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
申请公布号 WO2014062667(A1) 申请公布日期 2014.04.24
申请号 WO2013US65026 申请日期 2013.10.15
申请人 JANSSEN PHARMACEUTICA NV;LEONARD, KRISTI A. 发明人 LEONARD, KRISTI A.;BARBAY, KENT;EDWARDS, JAMES P.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;VENKATESAN, HARIHARAN;WANG, AIHUA;WOLIN, RONALD L.;WOODS, CRAIG R.;FOURIE, ANNE;XUE, XIAOHUA;MIRZADEGAN, TARANEH;GANAMET, KELLY LYNN
分类号 C07D401/14;A61K31/4709;A61P29/00;C07D401/06;C07D409/14;C07D413/06;C07D413/14;C07D417/14 主分类号 C07D401/14
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