发明名称 Compositions and Methods for Improving Toughness of Irradiated Sterilized Bone Allografts
摘要 The present invention relates to compositions, methods, kits and systems employing irradiation activated agents to improve or increase or prevent loss of toughness, work-to-fracture, post-yield toughness, fracture toughness and/or fatigue strength of a bone allograft on exposure to radiation. The irradiation activated agent can be an agent that increases crosslinking of collagen in bone during irradiation, for example ribose, 2-hydroxytetrahydropyran or ascorbate.
申请公布号 US2014112825(A1) 申请公布日期 2014.04.24
申请号 US201314055365 申请日期 2013.10.16
申请人 MOUNT SINAI HOSPITAL 发明人 WILLETT THOMAS
分类号 A61L2/00 主分类号 A61L2/00
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