| 发明名称 |
METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T |
| 摘要 |
<p>The present invention comprises compounds of Formula (I), wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.</p> |
| 申请公布号 |
CA2888210(A1) |
申请公布日期 |
2014.04.24 |
| 申请号 |
CA20132888210 |
申请日期 |
2013.10.15 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
LEONARD, KRISTI A.;BARBAY, KENT;EDWARDS, JAMES P.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;VENKATESAN, HARIHARAN;WANG, AIHUA;WOLIN, RONALD L.;WOODS, CRAIG R.;PIERCE, JOAN;GOLDBERG, STEVEN;FOURIE, ANNE;XUE, XIAOHUA |
| 分类号 |
C07D401/14;A61K31/4709;A61P29/00;C07D401/06;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D401/14 |
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