发明名称 |
Inhibitors of janus kinases |
摘要 |
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer. |
申请公布号 |
AU2008335761(B2) |
申请公布日期 |
2014.04.24 |
申请号 |
AU20080335761 |
申请日期 |
2008.12.09 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
YOUNG, JONATHAN R.;MACHACEK, MICHELLE R.;OTTE, RYAN D.;LIM, JONGWON;TAOKA, BRANDON MITSUO |
分类号 |
C07D471/04;A61K31/33;A61K31/555 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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