发明名称 COMPOUND, MANUFACTURING METHOD OF THE COMPOUND, MANUFACTURING METHOD OF ACETATE DERIVATIVE, MANUFACTURING METHOD OF ATORVASTATIN, AND RECOVERY METHOD OF ASYMMETRIC LIGAND
摘要 PROBLEM TO BE SOLVED: To provide an acetate derivative as a synthetic intermediate of atorvastatin, a novel compound capable of efficiently manufacturing the atorvastatin, a manufacturing method of the novel compound, an efficient manufacturing method of the acetate derivative using the novel compound, an efficient manufacturing method of atorvastatin using the novel compound, and a recovery method of an asymmetric ligand capable of recovering the asymmetric ligand used in manufacturing the atorvastatin.SOLUTION: There is provided a compound represented by the general formula (1), where Rrepresents either a protective group of a hydroxyl group or a hydrogen atom, and Rand Reach independently represent a protective group of an amino group.
申请公布号 JP2014073998(A) 申请公布日期 2014.04.24
申请号 JP20120223349 申请日期 2012.10.05
申请人 INSTITUTE OF MICROBIAL CHEMISTRY 发明人 SHIBAZAKI MASAKATSU;KUMAGAI NAOYA;KAWATO YUJI
分类号 C07C217/28;C07B61/00;C07C213/02;C07C215/10;C07C229/30;C07D207/34;C07D319/06 主分类号 C07C217/28
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