发明名称 MODIFIED 2' AND 3'-NUCLEOSIDE PRODRUGS FOR TREATING FLAVIVIRIDAE INFECTIONS
摘要 2′and/or 3′prodrugs of 1′, 2′, 3′or 4′-branched nucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.
申请公布号 US2014113880(A1) 申请公布日期 2014.04.24
申请号 US201414146520 申请日期 2014.01.02
申请人 IDENIX PHARMACEUTICALS, INC.;L'UNIVERSITE MONTPELLIER II;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFLQUE;UNIVERSITA DEGLI STUDI DI CAGLIARI 发明人 STORER RICHARD;GOSSELIN GILLES;SOMMADOSSI JEAN-PIERRE;LACOLLA PAOLO
分类号 C07H19/16 主分类号 C07H19/16
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