| 发明名称 |
IMPROVED PROCESS FOR PREPARATION OF REVAPRAZAN HYDROCHLORIDE |
| 摘要 |
<p>The present invention provides improved process for preparation of revaprazan hydrochloride (I) comprising reaction of l-methyl-l,2,3,4-tetrahydroisoquinoline (III) withcompound (VII) wherein R is a good leaving group selected from F, Cl, Br, I, (1), (2), (3) in presence of phase transfer catalyst and solvent to give revaprazan (VI) and followed by treatment with hydrochloride acid.</p> |
| 申请公布号 |
WO2014060908(A1) |
申请公布日期 |
2014.04.24 |
| 申请号 |
WO2013IB59225 |
申请日期 |
2013.10.09 |
| 申请人 |
LUPIN LIMITED |
发明人 |
ANSARI, SHAHID, AKHTAR;HIRPARA, HITIN, MAGANBHAI;BHATT, NIKHIL, SHASHIKANT;YADAV, ASHOK KESHAVLAL;PRAJAPATI, JITENDRAKUMAR, SHANTILAL;BARIA, REENABEN, RATANSING |
| 分类号 |
C07D401/04 |
主分类号 |
C07D401/04 |
| 代理机构 |
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