发明名称 |
USE OF HISTONE DEACETYLASE INHIBITORS FOR THE CARE OF PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE SYNDROMES |
摘要 |
The use of substances capable of inhibiting one or more enzymes of the histone deacetylase family (histone deacetylase inhibitors) for the therapeutic treatment of Philadelphia-negative myeloproliferative syndromes (polycythemia vera, essential thrombocythemia or idiopathic myelofibrosis) is described. The dosage of the above-mentioned substances is significantly lower than that normally used for the care of other tumour syndromes and may be from 10 to 150 mg/day/patient. |
申请公布号 |
EP2344253(B1) |
申请公布日期 |
2014.04.23 |
申请号 |
EP20090783251 |
申请日期 |
2009.09.21 |
申请人 |
ITALFARMACO SPA |
发明人 |
OLDONI, TIZIANO;MASCAGNI, PAOLO;RAMBALDI, ALESSANDRO;BARBUI, TIZIANO |
分类号 |
A61P11/10;A61K31/16;A61P35/02 |
主分类号 |
A61P11/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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