| 发明名称 |
PROCESS FOR THE PREPARATION OF CRYSTALLINE FORMS OF AGOMELATINE AND NOVEL POLYMORPH THEREOF |
| 摘要 |
The invention concerns a new process for the preparation of crystalline form of agomelatine from a solution of agomelatine in a solvent, characterized in that the agomelatine is crystallized by instantaneous precipitation from said solution, at a temperature equal to or below −10° C. |
| 申请公布号 |
EP2721001(A1) |
申请公布日期 |
2014.04.23 |
| 申请号 |
EP20110815571 |
申请日期 |
2011.12.29 |
| 申请人 |
LABORATORIO CHIMICO INTERNAZIONALE S.P.A. |
发明人 |
DE ANGELIS, BRUNO;GARIS, FARIS;DE GENNARO, SALVATORE;BERTOLINI, GIORGIO |
| 分类号 |
C07C231/24;C07C233/18 |
主分类号 |
C07C231/24 |
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