发明名称 |
PROCESS FOR THE PREPARATION AND SURFACE COATING OF PELLETS |
摘要 |
<p>The present invention is related to a process for the preparation of a pellet mass, wherein the premix containing one or more pharmaceutically active ingredient(s) is homogenized to obtain a starting powder mixture; spraying a granulating liquid onto said powder mixture, spheronizing, drying and fractionating the thus obtained particles, wherein the starting or partially pelletized powder mixture is blended with seeding pellets having identical or essentially similar composition but smaller average particle size than the particle size of the desired product fraction of the pellets. The pellets containing potassium chloride active ingredient obtained in the above process or according to a process known from the art can be provided with a controlled-release coating in a rolling-bed apparatus having non-perforated wall.</p> |
申请公布号 |
EP2023903(B1) |
申请公布日期 |
2014.04.23 |
申请号 |
EP20070733860 |
申请日期 |
2007.05.18 |
申请人 |
EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDO RESZVENYTARSASAG |
发明人 |
FARAGO, GABOR;FAZEKAS, PATRIK;GUENTHER, GABOR;KOCSIS, LASZLO;PATAKI, KAROLY |
分类号 |
A61K9/16 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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