| 摘要 |
<p>An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I):
wherein R 1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa) :
wherein R 4 is lower alkyl, R 5 is lower alkylene, and m is an integer of 1 to 6;
R 2 is lower alkyl optionally substituted with phenyl; and
R 3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.</p> |
