发明名称 |
Compositions and methods for delivering inhibitory oligonucleotides |
摘要 |
The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject. |
申请公布号 |
US8703921(B2) |
申请公布日期 |
2014.04.22 |
申请号 |
US20090988148 |
申请日期 |
2009.04.15 |
申请人 |
ARYA BIRA;OLKHANUD PUREVDORJ;ESPINOZA JUAN;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES |
发明人 |
ARYA BIRA;OLKHANUD PUREVDORJ;ESPINOZA JUAN |
分类号 |
C07K5/00;A61K39/00;C07H21/04 |
主分类号 |
C07K5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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